| No. | 049 |
| Project Title | Ex vivo dry eye model as an alternative to animal testing in pharmacological screenings |
| Project Leader | Dr. Felix Spöler & Prof. Dr. Norbert Schrage |
| Organisation | RWTH Aachen & ACTO, Germany |
| Duration | 07/2011 - 12/2011 |
| No. | 049 |
| Project Title | Ex vivo dry eye model as an alternative to animal testing in pharmacological screenings |
| Project Leader | Dr. Felix Spöler & Prof. Dr. Norbert Schrage |
| Organisation | RWTH Aachen & ACTO, Germany |
| Duration | 07/2011 - 12/2011 |
| No. | 048 |
| Project Title | Human thromobocyte concentrates as substitutes for animal-derived serum in stem cell cultures for in vitro toxicity testing |
| Project Leader | Prof. Dr. Gerhard Gstraunthaler |
| Organisation | University of Innsbruck (Austria) |
| Duration | 05/2011 - 04/2013 |
| No. | 047 |
| Project Title | Development of an otic stem cell based model of the inner ear: An in vitro model for drug development in the field of hearing loss |
| Project Leader | PD Dr. Hubert Löwenheim |
| Organisation | University of Tübingen (Germany) |
| Duration | 04/2011 - 09/2012 |
| No. | 046 |
| Project Title | Analysis of EU-legislation in terms of consistency and state-of-the-art regarding the implementation of the 3Rs in the data requirements to identify potential for further improvement |
| Project Leader | Roman Kolar |
| Organisation | Akademie für Tierschutz, Neubiberg (Germany) |
| Duration | 04/2011 - 09/2011 |
| No. | 045 |
| Project Title | Development of a 3D flow through model for long-term culture of polarized hepatocytes (-like cells) in vitro |
| Project Leader | Dr. Sabrina Ehnert & Prof. Dr. Andreas K. Nüssler |
| Organisation | University of Tübingen (Germany) |
| Duration | 04/2011 - 03/2013 |
| No. | 044 |
| Project Title | Development of an in vitro method for the determination of tetanus toxicity in tetanus vaccines |
| Project Leader | Dr. Karin Weisser, Dr. Beate Krämer |
| Organisation | Paul-Ehrlich-Institut, Langen (Germany) |
| Duration | 02/2011 - 04/2012 |
| No. | 043 |
| Project Title | Development of an in vitro test system for cancerogenicity testing of chemicals with high throughput |
| Project Leader | Prof. Dr. Pablo Steinberg |
| Organisation | TiHo Hannover |
| Duration | 12/2010 - 11/2011 |
| No. | 042 |
| Project Title | Development of a Reverse Transcriptase Real Time-PCR assay for the detection of Clostridium botulinum Typ A, B, E and F neurotoxin-production in foods as an alternative method to the mouse bioassay |
| Project Leader | Prof. Dr. Michael Bülte |
| Organisation | Universität Giessen |
| Duration | 12/2007 - 11/2010 |
| No. | 041 |
| Project Title | Development of an in vitro model of rheumatoid joint destruction by using cross-linked fluorescent-labeled collagen matrices |
| Project Leader | Prof. Dr. Thomas Pap |
| Organisation | Universität Münster |
| Duration | 10/2007 - 09/2009 |
| No. | 040 |
| Project Title | Improved genotoxicity tests with the Phenion® Full Thickness Skin Model |
| Project Leader | Dr. Kerstin Reisinger |
| Organisation | Phenion GmbH & Co. KG, Düsseldorf |
| Duration | 09/2007 - 08/2009 |