P-071

Brain-Organoid-Tumor Hybrids – an in vitro model for human brain tumor analysis and drug testing

Prof. Philipp Koch & Prof. Frank Winkler,
Hector Institute for Translational Brain Research, Zentralinstitut für Seelische Gesundheit, Universitätsklinikum Heidelberg, Deutsches Krebsforschungszentrum,
Mannheim & Heidelberg

07/2020-12/2021 

Human brain tumors are difficult to modulate in cell culture. We present an innovative alternative system in which the brain tumors are cultivated in organoids (3D tissue structures made from stem cells) instead of in experimental animals.

[Translate to English:] Projektbeschreibung Absatz 1

Projektbeschreibung Absatz 2

Fig. 1:   The brain-organoid tumor hybrid model.
Tumor cells grow into the organoids and form networks within the organoids.

Institutions

Prof. Dr. Philipp Koch
Hector Institute for Translational Brain Research,
Zentralinstitut für Seelische Gesundheit
J5, 68159 Mannheim

Prof. Dr. Frank Winkler
Universitätsklinikum Heidelberg,
Deutsches Krebsforschungszentrum,
Im Neuenheimer Feld 400, 69120 Heidelberg

Duration

07/2020 - 12/2021