Supported projects

To avoid and reduce animal testing or the burden on laboratory animals, the set foundation is active in three areas: promoting scientific projects with a 3R focus, promoting communication in this area, and supporting education and training.

• P-079 Duration: 05/2023 - 04/2027

  Defining and controlling drivers of phenotypic variability in stembryos, pluripotent stem-cell-based models of mouse and human embryo development

  Project management: Dr. Jesse-Valentijn Veenvliet

  Organisation: Max Planck Institute of Molecular Cell Biology and Genetics Pfotenhauerstrasse 108 01307 Dresden

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• P-078 Duration: 01/2023 - 12/2024

  Spectroscopic identification of vaccine components

  Project management: PD Dr. Christel Kamp

  Organisation: Paul-Ehrlich-Institut Federal Institute for Vaccines and Biomedicines Paul-Ehrlich-Str. 51-59 63225 Langen

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• P-077 Duration: 03/2022 - 02/2024

  Xeno-free in vitro 3D Modeling of Synovitis

  Project management: Dr. Alexandra Damerau, Dr. Timo Gaber

  Organisation: Charité-Universitätsmedizin Berlin Department of Rheumatology and Clinical Immunology Charitéplatz 1 10117 Berlin

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• P-076 Duration: 10/2021 - 09/2022

  Tissue-engineered 3D cornea model to simulate wound healing and scarring of the cornea

  Project management: Dr. Daniel Kampik

  Organisation: Dr. med. Daniel Kampik & Dr. med. Ann-Katrin Regensburger: Universitätsklinikum Würzburg Institut für Augenheilkunde Dr. rer. nat. Christian Lotz: Fraunhofer ISC Würzburg Translationszentrum für Regenerative Therapien

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• P-075 Duration: 10/2021 - 09/2023

  Bioprinting of a 3D tumor model

  Project management: Prof. Dr. Jens Kurreck

  Organisation: Technische Universität Berlin Institut für Biotechnologie Fachgebiet Angewandte Biochemie, TIB 4/3-2 Gustav-Meyer-Allee 25 13355 Berlin

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• P-074 Duration: 02/2021 - 01/2023

  Development of a human 3D tumor microenvironment-on-chip model for personalized drug testing on a pancreatic adenocarcinoma

  Project management: Prof. Dr. rer. nat. Nicole Teusch, Dr. rer. nat. Knut Rennert

  Organisation: Institute of Pharmaceutical Biology and Biotechnology Heinrich Heine University Düsseldorf Dynamic42 GmbH Winzerlaer Straße 2 Jena

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• P-073 Duration: 07/2021 - 01/2024

  3D-Bioprinting of bacterial biofilms on human lung cell monolayers as an in vitro model of a chronic lung infection

  Project management: Prof. Dr. Claus-Michael Lehr

  Organisation: Research group Prof. Dr. Claus-Michael Lehr "Drug Delivery Across Biological Barriers" Helmholtz-Institute for Pharmaceutical Research Saarland Campus E8 1 66123 Saarbrücken

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• P-072 Duration: 10/2020 - 06/2022

  Pilot study: Culture of Care as the cornerstone of effective 3Rs-implementation

  Project management: Dr. Katharina Ameli, Prof. Dr. med. vet. Stephanie Krämer

  Organisation: ICAR3R - Interdisciplinary Centre for 3Rs in Animal Research Justus-Liebig-Universität Gießen Frankfurter Straße 110 35392 Gießen

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• P-071 Duration: 07/2020 - 12/2021

  Brain-organoid-tumour hybrids – an in vitro model for the analysis of human brain tumours and drug testing

  Project management: Prof. Dr. Philipp Koch, Prof. Dr. Frank Winkler

  Organisation: Prof. Dr. Philipp Koch Hector Institute for Translational Brain Research Zentralinstitut für Seelische GesundheitJ5 68159 Mannheim Prof. Dr. Frank Winkler Universitätsklinikum Heidelberg Deutsches Krebsforschungszentrum Im Neuenheimer Feld 400 69120 Heidelberg

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• P-070 Duration: 05/2020 - 10/2022

  VitroInfect – Establishment of an in vitro biofilm platform model for tissue infections

  Project management: Prof. Dr. Maike Windbergs

  Organisation: Research group Prof. Dr. Maike Windbergs “Drug Delivery and 3R-Models” Goethe University Frankfurt Institute for Pharmaceutical Technology and Buchmann Institute of Molecular Life Sciences Max-von-Laue-Str. 9 60438 Frankfurt am Main

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